Description
Cell Biology
Structure and function of cell and its organelles (nucleus, plasma membrane, mitochondria, Golgi Bodies, endoplasmic reticulum, ribosomes, and lysosomes), cell division (mitosis and meiosis), mitotic spindle and mitotic apparatus, chromosome movements, chromosome type polytene and lampbrush,organization of chromatin, heterochromatin, Cell cycle regulation
Nucleic acid topology, DNA motif, DNA replication, transcription, RNA processing, translation, protein foldings and transport
Genetics
Modern concept of gene, split gene, genetic regulation, genetic code
Sex chromosomes and their evolution, sex determination in Drosophila and man
Mendel’s laws of inheritance, recombination, linkage, multiple alleles, genetics of blood groups,pedigree analysis, hereditary diseases in man
Mutations and mutagenesis
Recombinant DNA technology; plasmid, cosmid, artificial chromosomes as vectors, transgenic,DNA cloning and whole animal cloning (principles and methods)
Gene regulation and expression in prokaryotes and eukaryotes
Signal molecules, cell death, defects in signaling pathway and consequences
RFLP, RAPD and AFLP and application of RFLP in DNA fingerprinting, ribozyme technologies,human genome project, genomics and proteomics
Biochemistry
Structure and role of carbohydrates, fats, fatty acids and cholesterol, proteins and amino-acids,nucleic acids. Bioenergetics
Glycolysis and Kreb cycle, oxidation and reduction, oxidative phosphorylation, energy conservation and release, ATP cycle, cyclic AMP – its structure and role
Hormone classification (steroid and peptide hormones), biosynthesis and functions
Enzymes: types and mechanisms of action
Vitamins and coenzymes
Immunoglobulin and immunity
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